| Jonathan Liebesman | ||
| Josh Appelbaum | ... | (written by) & |
| André Nemec | ... | (written by) and |
| Evan Daugherty | ... | (written by) |
| Peter Laird | ... | (based on the Teenage Mutant Ninja Turtles characters created by) and |
| Kevin Eastman | ... | (based on the Teenage Mutant Ninja Turtles characters created by) |
| Tanit Jitnukul | ||
 | Kessarin Ektawatkul | Dao | |
| Nirut Saosudchart | Niphon | |
| Nawarat Techarathanaprasert | Pad | |
| Sarunyu Wongkrachang | Captain Rith | |
| Marc Nemcik | ||
| Daniel Christian | ... | producer |
| Robert Greene | ... | producer |
| Suzy le Bel | ... | producer |
| Marc Nemcik | ... | producer |
| Alexandra Watkins | ... | producer |
| Stacey Woelfel | ... | producer |
| Alexandra Watkins | ||
| Marc Nemcik | ||
| Dustin Browder | ||
| Chris Metzen | ||
| James M. Waugh | ... | (as James Waugh) |
 | Patrick Seitz | Artanis (voice) | |
 | Travis Willingham | Karax (voice) | |
 | Rachel Robinson | Vorazun (voice) | |
 | Tricia Helfer | Sarah Kerrigan / Queen of Blades (voice) | |
 | Fred Tatasciore | Zeratul / Swann / Marauder (voice) | |
 | Robert Clotworthy | Jim Raynor (voice) | |
 | Claudia Christian | Rohanna (voice) (as Claudia Christain) | |
 | Marc Graue | Fenix (voice) | |
 | John de Lancie | Alarak (voice) | |
 | Nika Futterman | Zagara / Zerg Queen (voice) | |
 | Rick D. Wasserman | Amon (voice) | |
 | Mary Elizabeth McGlynn | Talis (voice) | |
 | Michael Dorn | Ouros / Xel'naga (voice) | |
 | Cree Summer | Selendis (voice) | |
 | Josh Keaton | Valerian Mengsk (voice) | |
| Victor Brandt | Alexi Stukov (voice) | |
 | Brian Bloom | Matt Horner (voice) | |
 | April Stewart | Additional Voices (voice) | |
 | Cam Clarke | Additional Voices (voice) | |
 | Christopher Judge | Additional Voices (voice) | |
 | Courtenay Taylor | Additional Voices (voice) | |
 | Darin De Paul | Additional Voices (voice) | |
 | David Boat | Additional Voices (voice) | |
| Dave Fouquette | Additional Voices (voice) | |
| Dave B. Mitchell | Additional Voices (voice) | |
 | David Lodge | Additional Voices (voice) | |
 | Debra Wilson | Additional Voices (voice) | |
| Ethan Sawyer | Additional Voices (voice) | |
 | Gerald C. Rivers | Additional Voices (voice) | |
 | Gideon Emery | Tal'darim Executor (voice) | |
 | Grey Griffin | Additional Voices (voice) | |
 | Guerin Barry | Additional Voices (voice) | |
 | Ike Amadi | Additional Voices (voice) | |
 | Imari Williams | Additional Voices (voice) | |
 | Isaac C. Singleton Jr. | Additional Voices (voice) | |
 | Jamieson Price | Additional Voices (voice) | |
| Jim Miller | Additional Voices (voice) | |
 | John DiMaggio | Additional Voices (voice) | |
 | Jonathan Adams | Additional Voices (voice) | |
 | Julianne Buescher | Additional Voices (voice) | |
 | Karen Strassman | Additional Voices (voice) | |
 | Kari Wahlgren | Additional Voices (voice) | |
 | Marc Worden | Additional Voices (voice) | |
| Mark Mintz | Additional Voices (voice) | |
 | Maury Sterling | Additional Voices (voice) | |
 | Max Mittelman | Stone (voice) | |
 | Misty Lee | Additional Voices (voice) | |
 | Neil Kaplan | Additional Voices (voice) | |
| Patrick Pinney | Additional Voices (voice) (as Pat Pinney) | |
 | Paul Eiding | Additional Voices (voice) | |
 | Peter Giles | Additional Voices (voice) | |
 | Rachael MacFarlane | Additional Voices (voice) | |
 | Robert Torti | Additional Voices (voice) | |
 | Robin Atkin Downes | Additional Voices (voice) | |
 | Stephen Stanton | Mal'ash (voice) | |
 | Sumalee Montano | Additional Voices (voice) | |
| Rest of cast listed alphabetically: | |||
 | Charlet Chung | D.Va (voice) | |
| Marqus Kane | Fenix Win'thar | |
 | Kiff VandenHeuvel | Additional Voices (voice) | |
| Anna Graves | Dominion Officer (voice) (uncredited) | |
| Wendy Berry Campbell | ... | producer: Intro Cinematic (as Wendy Berry) |
| Eric Kieron Davis | ... | cinematics producer |
| Andrea Toyias | ||
| Dwight Hwang | ... | storyboard artist |
| Yunhao Zhang | ... | storyboard artist intern (uncredited) |
| Gregg Barbanell | ... | foley artist |
| Christopher Barnett | ... | cinematic re-recording mixer |
| Thomas C. Brewer | ... | sound re-recording mixer: cinematics |
| Russell Brower | ... | audio director |
| Ed Cerrato | ... | sound designer |
| Evan T. Chen | ... | sound supervisor |
| Dennis Crabtree | ... | sound post-production producer |
| Alexander Ephraim | ... | sound designer |
| Isaac Hammons | ... | dialogue editor |
| Caroline Hernandez | ... | supervising sound editor |
| Darrin Mann | ... | foley editor |
| Paul Menichini | ... | supervising sound editor |
| Tim Nielsen | ... | additional cinematic sound design (as Timothy Nielsen) |
| Jacob Ortiz | ... | dialogue editor |
| Larry Peacock | ... | sound designer |
| Gary Rizzo | ... | cinematic re-recording mixer |
| David Rovin | ... | sound editor |
| Peter Steinbach | ... | VO Designer |
| John Thomas | ... | sound designer: cinematics |
| Daniel Timmons | ... | adr mixer |
| Andrea Toyias | ... | dialogue editor |
| Christopher Garcia | ... | cinematic software engineer |
| Eric Grimenstein | ... | senior cinematic effects artist |
| Piotrek Krawczyk | ... | lead technical director |
| Brett McConnell | ... | lead lighting artist |
| Thomas V. Thompson II | ... | technology: software engineer |
| James Wright | ... | in-game cinematic fx artist |
| Ronny Kim | ... | Senior Cinematic Animator |
| Careena Kingdom | ... | senior animator |
| Casey McDermott | ... | cinematic animator |
| Matt Onheiber | ... | cinematic animator |
| Glenn Ramos | ... | lead animator: Cinematics |
| Doosun Shin | ... | animator |
| Selig Tobiason | ... | animator |
| Rebecca Lilienfeld | ... | assistant editor |
| Neal Acree | ... | supervising music editor |
| Jaroslav Beck | ... | music editor |
| Kory Kruckenberg | ... | assistant score engineer: Pro Tools Engineer |
| John Kurlander | ... | music recording engineer / score mixer |
| Thierry Malet | ... | Composer: Additional Music / composer: Trailer Music |
| Robert Puff | ... | music preparation |
| David Sabee | ... | music contractor |
| Diego Stocco | ... | featured soloist: Synthesizer |
| Michael Chu | ... | blizzard development family |
| Doug Fitchett | ... | customer support |
| Geoff Fraizer | ... | web editor |
| Dana Licht | ... | support staff |
| Nigel Nikitovich | ... | compatibility analyst |
| Rachel Richmond | ... | in-game cinematics associate producer |
| Andrea Toyias | ... | voice director |
| Robert R. Van Dusen | ... | vp: Information Technology (as Robert Van Dusen) |
| James M. Waugh | ... | story director |
